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Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization
No clinically validated biomarkers exist to image tumor responses to anti-angiogenic therapy. Here we report the utility of hyperpolarized (13)C magnetic resonance spectroscopy (MRS) to detect the early metabolic effects of anti-VEGF therapy. In two colorectal cancer xenograft models displaying diff...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378497/ https://ncbi.nlm.nih.gov/pubmed/22223844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2795 |
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