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An Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling
The protein kinase Fused (Fu) is an integral member of the Hedgehog (Hh) signaling pathway. Although genetic studies demonstrate that Fu is required for the regulation of the Hh pathway, the mechanistic role that it plays remains largely unknown. Given our difficulty in developing an in vitro kinase...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529051/ https://ncbi.nlm.nih.gov/pubmed/15542847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10397-10405.2004 |
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