An Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling

The protein kinase Fused (Fu) is an integral member of the Hedgehog (Hh) signaling pathway. Although genetic studies demonstrate that Fu is required for the regulation of the Hh pathway, the mechanistic role that it plays remains largely unknown. Given our difficulty in developing an in vitro kinase...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Ascano, Manuel, Robbins, David J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2004
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529051/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10397-10405.2004
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