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An Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling

The protein kinase Fused (Fu) is an integral member of the Hedgehog (Hh) signaling pathway. Although genetic studies demonstrate that Fu is required for the regulation of the Hh pathway, the mechanistic role that it plays remains largely unknown. Given our difficulty in developing an in vitro kinase...

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Bibliografische gegevens
Hoofdauteurs: Ascano, Manuel, Robbins, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC529051/
https://ncbi.nlm.nih.gov/pubmed/15542847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10397-10405.2004
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