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The Carboxyl-Terminal Domain of the Protein Kinase Fused Can Function as a Dominant Inhibitor of Hedgehog Signaling

The secreted protein hedgehog (Hh) plays a critical role in the developmental patterning of multiple tissues. In Drosophila melanogaster, a cytosolic multiprotein signaling complex appears necessary for Hh signaling. Genes that encode components of this Hh signaling complex (HSC) were originally ide...

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Detalhes bibliográficos
Main Authors: Ascano, Manuel, Nybakken, Kent E., Sosinski, Janek, Stegman, Melanie A., Robbins, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134684/
https://ncbi.nlm.nih.gov/pubmed/11839821
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