The Carboxyl-Terminal Domain of the Protein Kinase Fused Can Function as a Dominant Inhibitor of Hedgehog Signaling

The secreted protein hedgehog (Hh) plays a critical role in the developmental patterning of multiple tissues. In Drosophila melanogaster, a cytosolic multiprotein signaling complex appears necessary for Hh signaling. Genes that encode components of this Hh signaling complex (HSC) were originally ide...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ascano, Manuel, Nybakken, Kent E., Sosinski, Janek, Stegman, Melanie A., Robbins, David J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1555-1566.2002
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