A quantized mechanism for activation of pannexin channels

Pannexin 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for purinergic signalling, which is involved in diverse physiological processes such as apoptosis, inflammation, blood pressure regulation, and cancer progression and metastasis. Here we explore the...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Chiu, Yu-Hsin, Jin, Xueyao, Medina, Christopher B., Leonhardt, Susan A., Kiessling, Volker, Bennett, Brad C., Shu, Shaofang, Tamm, Lukas K., Yeager, Mark, Ravichandran, Kodi S., Bayliss, Douglas A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290276/
https://ncbi.nlm.nih.gov/pubmed/28134257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14324
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