A quantized mechanism for activation of pannexin channels

Pannexin 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for purinergic signalling, which is involved in diverse physiological processes such as apoptosis, inflammation, blood pressure regulation, and cancer progression and metastasis. Here we explore the...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chiu, Yu-Hsin, Jin, Xueyao, Medina, Christopher B., Leonhardt, Susan A., Kiessling, Volker, Bennett, Brad C., Shu, Shaofang, Tamm, Lukas K., Yeager, Mark, Ravichandran, Kodi S., Bayliss, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290276/
https://ncbi.nlm.nih.gov/pubmed/28134257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14324
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