A quantized mechanism for activation of pannexin channels

Pannexin 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for purinergic signalling, which is involved in diverse physiological processes such as apoptosis, inflammation, blood pressure regulation, and cancer progression and metastasis. Here we explore the...

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Vydáno v:Nat Commun
Hlavní autoři: Chiu, Yu-Hsin, Jin, Xueyao, Medina, Christopher B., Leonhardt, Susan A., Kiessling, Volker, Bennett, Brad C., Shu, Shaofang, Tamm, Lukas K., Yeager, Mark, Ravichandran, Kodi S., Bayliss, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290276/
https://ncbi.nlm.nih.gov/pubmed/28134257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14324
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