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The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis

Stereochemical control is critical in natural product biosynthesis. For ribosomally synthesized and post-translationally modified peptides (RiPPs), the mechanism(s) by which stereoselectivity is achieved is still poorly understood. In this work, we focused on the stereoselective lanthionine synthesi...

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Publicado en:ACS Chem Biol
Autores principales: Tang, Weixin, Thibodeaux, Gabrielle N., van der Donk, Wilfred A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289929/
https://ncbi.nlm.nih.gov/pubmed/27348535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00397
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