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Synthesis and Bioactivity of Diastereomers of the Virulence Lanthipeptide Cytolysin
Cytolysin, a two-component lanthipeptide comprising cytolysin S (CylL(S)″) and cytolysin L (CylL(L)″), is the only family member to exhibit lytic activity against mammalian cells, in addition to synergistic antimicrobial activity. A subset of the thioether crosslinks of CylL(S)″ and CylL(L)″ have LL...
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| Publicado no: | Org Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5269379/ https://ncbi.nlm.nih.gov/pubmed/27934350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b03246 |
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