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The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis

Stereochemical control is critical in natural product biosynthesis. For ribosomally synthesized and post-translationally modified peptides (RiPPs), the mechanism(s) by which stereoselectivity is achieved is still poorly understood. In this work, we focused on the stereoselective lanthionine synthesi...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Tang, Weixin, Thibodeaux, Gabrielle N., van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289929/
https://ncbi.nlm.nih.gov/pubmed/27348535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00397
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