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The Sequence of the Enterococcal Cytolysin Imparts Unusual Lanthionine Stereochemistry

The enterococcal cytolysin is a two-component lantibiotic of unknown structure with hemolytic activity that is important for virulence. We prepared cytolysin by co-expression of each precursor peptide with the synthetase CylM in E. coli, and characterized its structure. Surprisingly, cytolysin is th...

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Bibliografski detalji
Glavni autori: Tang, Weixin, van der Donk, Wilfred A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578037/
https://ncbi.nlm.nih.gov/pubmed/23314913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1162
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