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The Importance of the Leader Sequence for Directing Lanthionine Formation in Lacticin 481
Lantibiotics are post-translationally modified peptide antimicrobial agents that are synthesized with an N-terminal leader sequence and a C-terminal propeptide. Their maturation involves enzymatic dehydration of Ser and Thr residues in the precursor peptide to generate unsaturated amino acids, which...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574844/ https://ncbi.nlm.nih.gov/pubmed/18570437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800277d |
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