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Response to Comments on “Extreme electric fields power catalysis in the active site of ketosteroid isomerase”
Natarajan et al. and Chen and Savidge comment that comparing the electric field in ketosteroid isomerase’s (KSI’s) active site to zero overestimates the catalytic effect of KSI’s electric field because the reference reaction occurs in water, which itself exerts a sizable electrostatic field. To comp...
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| Publicado en: | Science |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289113/ https://ncbi.nlm.nih.gov/pubmed/26315428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab1627 |
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