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The Case of Ketosteroid Isomerase

Structures of enzymes invariably reveal the proximity of acidic and basic residues to reactive sites on the substrate, so it is natural and common to suggest that enzymes employ concerted mechanisms to catalyze their difficult reactions. Ketosteroid Isomerase (KSI) has served as a paradigm of enzyma...

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Detalhes bibliográficos
Main Authors: Fried, Stephen D., Boxer, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257410/
https://ncbi.nlm.nih.gov/pubmed/22148842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp210544w
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