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Quantitative, directional measurement of electric field heterogeneity in the active site of ketosteroid isomerase

Understanding the electrostatic forces and features within highly heterogeneous, anisotropic, and chemically complex enzyme active sites and their connection to biological catalysis remains a longstanding challenge, in part due to the paucity of incisive experimental probes of electrostatic properti...

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Bibliografiske detaljer
Main Authors: Fafarman, Aaron T., Sigala, Paul A., Schwans, Jason P., Fenn, Timothy D., Herschlag, Daniel, Boxer, Steven G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277571/
https://ncbi.nlm.nih.gov/pubmed/22308339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111566109
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