Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

BACKGROUND: Here we integrate verified signals from previous genetic association studies with gene expression and pathway analysis for discovery of new candidate genes and signaling networks, relevant for rheumatoid arthritis (RA). METHOD: RNA-sequencing-(RNA-seq)-based expression analysis of 377 ge...

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發表在:Arthritis Res Ther
Main Authors: Shchetynsky, Klementy, Diaz-Gallo, Lina-Marcella, Folkersen, Lasse, Hensvold, Aase Haj, Catrina, Anca Irinel, Berg, Louise, Klareskog, Lars, Padyukov, Leonid
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288892/
https://ncbi.nlm.nih.gov/pubmed/28148290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1220-5
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