IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis

BACKGROUND: Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The glycosylation status of immunoglobulin G (IgG) is altered in RA and influenced by MTX treatment. We aimed to further investigate if IgG gly...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Lundström, Susanna L., Hensvold, Aase H., Rutishauser, Dorothea, Klareskog, Lars, Ytterberg, A. Jimmy, Zubarev, Roman A., Catrina, Anca I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549282/
https://ncbi.nlm.nih.gov/pubmed/28793911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1389-7
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