Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

BACKGROUND: Here we integrate verified signals from previous genetic association studies with gene expression and pathway analysis for discovery of new candidate genes and signaling networks, relevant for rheumatoid arthritis (RA). METHOD: RNA-sequencing-(RNA-seq)-based expression analysis of 377 ge...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Shchetynsky, Klementy, Diaz-Gallo, Lina-Marcella, Folkersen, Lasse, Hensvold, Aase Haj, Catrina, Anca Irinel, Berg, Louise, Klareskog, Lars, Padyukov, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288892/
https://ncbi.nlm.nih.gov/pubmed/28148290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1220-5
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