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Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

BACKGROUND: Here we integrate verified signals from previous genetic association studies with gene expression and pathway analysis for discovery of new candidate genes and signaling networks, relevant for rheumatoid arthritis (RA). METHOD: RNA-sequencing-(RNA-seq)-based expression analysis of 377 ge...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: Shchetynsky, Klementy, Diaz-Gallo, Lina-Marcella, Folkersen, Lasse, Hensvold, Aase Haj, Catrina, Anca Irinel, Berg, Louise, Klareskog, Lars, Padyukov, Leonid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288892/
https://ncbi.nlm.nih.gov/pubmed/28148290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1220-5
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