Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety

Oxidative stress is known to play an important role in oral cancer development. In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis. We first showed that Nrf2 activation and ox...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Lan, Aixian, Li, Wenjun, Liu, Yao, Xiong, Zhaohui, Zhang, Xinyan, Zhou, Shanshan, Palko, Olesya, Chen, Hao, Kapita, Mayanga, Prigge, Justin R., Schmidt, Edward E., Chen, Xin, Sun, Zheng, Chen, Xiaoxin Luke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288201/
https://ncbi.nlm.nih.gov/pubmed/27447968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10609
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge