Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety

Oxidative stress is known to play an important role in oral cancer development. In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis. We first showed that Nrf2 activation and ox...

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發表在:Oncotarget
Main Authors: Lan, Aixian, Li, Wenjun, Liu, Yao, Xiong, Zhaohui, Zhang, Xinyan, Zhou, Shanshan, Palko, Olesya, Chen, Hao, Kapita, Mayanga, Prigge, Justin R., Schmidt, Edward E., Chen, Xin, Sun, Zheng, Chen, Xiaoxin Luke
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288201/
https://ncbi.nlm.nih.gov/pubmed/27447968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10609
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