Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety

Oxidative stress is known to play an important role in oral cancer development. In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis. We first showed that Nrf2 activation and ox...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Lan, Aixian, Li, Wenjun, Liu, Yao, Xiong, Zhaohui, Zhang, Xinyan, Zhou, Shanshan, Palko, Olesya, Chen, Hao, Kapita, Mayanga, Prigge, Justin R., Schmidt, Edward E., Chen, Xin, Sun, Zheng, Chen, Xiaoxin Luke
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288201/
https://ncbi.nlm.nih.gov/pubmed/27447968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10609
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