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Intracranial AAV‐IFN‐β gene therapy eliminates invasive xenograft glioblastoma and improves survival in orthotopic syngeneic murine model

The highly invasive property of glioblastoma (GBM) cells and genetic heterogeneity are largely responsible for tumor recurrence after the current standard‐of‐care treatment and thus a direct cause of death. Previously, we have shown that intracranial interferon‐beta (IFN‐β) gene therapy by locally a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: GuhaSarkar, Dwijit, Neiswender, James, Su, Qin, Gao, Guangping, Sena‐Esteves, Miguel
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288127/
https://ncbi.nlm.nih.gov/pubmed/28098415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12020
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