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Systemic AAV9-IFNβ gene delivery treats highly invasive glioblastoma

BACKGROUND: Complete surgical removal of all glioblastoma (GBM) cells is impossible due to extensive infiltration into brain parenchyma that ultimately leads to tumor recurrence. The current standard of care affords modest improvements in survival. New therapeutic interventions are needed to prevent...

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Publicat a:Neuro Oncol
Autors principals: GuhaSarkar, Dwijit, Su, Qin, Gao, Guangping, Sena-Esteves, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063516/
https://ncbi.nlm.nih.gov/pubmed/27194146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now097
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