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Systemic AAV9-IFNβ gene delivery treats highly invasive glioblastoma

BACKGROUND: Complete surgical removal of all glioblastoma (GBM) cells is impossible due to extensive infiltration into brain parenchyma that ultimately leads to tumor recurrence. The current standard of care affords modest improvements in survival. New therapeutic interventions are needed to prevent...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: GuhaSarkar, Dwijit, Su, Qin, Gao, Guangping, Sena-Esteves, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063516/
https://ncbi.nlm.nih.gov/pubmed/27194146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now097
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