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Unidirectional translocation from recognition site and a necessary interaction with DNA end for cleavage by Type III restriction enzyme

Type III restriction enzymes have been demonstrated to require two unmethylated asymmetric recognition sites oriented head-to-head to elicit double-strand break 25–27 bp downstream of one of the two sites. The proposed DNA cleavage mechanism involves ATP-dependent DNA translocation. The sequence con...

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Xehetasun bibliografikoak
Egile Nagusiak: Raghavendra, Nidhanapati K., Rao, Desirazu N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC528788/
https://ncbi.nlm.nih.gov/pubmed/15501920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh899
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