DNA looping and translocation provide an optimal cleavage mechanism for the type III restriction enzymes

EcoP15I is a type III restriction enzyme that requires two recognition sites in a defined orientation separated by up to 3.5 kbp to efficiently cleave DNA. The mechanism through which site-bound EcoP15I enzymes communicate between the two sites is unclear. Here, we use atomic force microscopy to stu...

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Detaylı Bibliyografya
Asıl Yazarlar: Crampton, Neal, Roes, Stefanie, Dryden, David T F, Rao, Desirazu N, Edwardson, J Michael, Henderson, Robert M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952222/
https://ncbi.nlm.nih.gov/pubmed/17660745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601807
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