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Unidirectional translocation from recognition site and a necessary interaction with DNA end for cleavage by Type III restriction enzyme
Type III restriction enzymes have been demonstrated to require two unmethylated asymmetric recognition sites oriented head-to-head to elicit double-strand break 25–27 bp downstream of one of the two sites. The proposed DNA cleavage mechanism involves ATP-dependent DNA translocation. The sequence con...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC528788/ https://ncbi.nlm.nih.gov/pubmed/15501920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh899 |
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