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DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes.

Type I restriction enzymes bind to a specific DNA sequence and subsequently translocate DNA past the complex to reach a non-specific cleavage site. We have examined several potential blocks to DNA translocation, such as positive supercoiling or a Holliday junction, for their ability to trigger DNA c...

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Autors principals: Janscak, P, MacWilliams, M P, Sandmeier, U, Nagaraja, V, Bickle, T A
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171343/
https://ncbi.nlm.nih.gov/pubmed/10228175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2638
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