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DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes.
Type I restriction enzymes bind to a specific DNA sequence and subsequently translocate DNA past the complex to reach a non-specific cleavage site. We have examined several potential blocks to DNA translocation, such as positive supercoiling or a Holliday junction, for their ability to trigger DNA c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171343/ https://ncbi.nlm.nih.gov/pubmed/10228175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2638 |
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