Single amino acid substitutions in the HsdR subunit of the type IB restriction enzyme EcoAI uncouple the DNA translocation and DNA cleavage activities of the enzyme.

Lignende værker

• DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes.
  af: Janscak, P, et al.
  Udgivet: (1999)
• The HsdR subunit of R.EcoR124II: cloning and over-expression of the gene and unexpected properties of the subunit.
  af: Zinkevich, V, et al.
  Udgivet: (1997)
• On the DNA cleavage mechanism of Type I restriction enzymes
  af: Jindrova, Eva, et al.
  Udgivet: (2005)
• HsdR Subunit of the Type I Restriction-Modification Enzyme EcoR124I: Biophysical Characterisation and Structural Modelling
  af: Obarska-Kosinska, Agnieszka, et al.
  Udgivet: (2008)
• Translocation and specific cleavage of bacteriophage T7 DNA in vivo by EcoKI
  af: García, L. René, et al.
  Udgivet: (1999)