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DNA looping and translocation provide an optimal cleavage mechanism for the type III restriction enzymes
EcoP15I is a type III restriction enzyme that requires two recognition sites in a defined orientation separated by up to 3.5 kbp to efficiently cleave DNA. The mechanism through which site-bound EcoP15I enzymes communicate between the two sites is unclear. Here, we use atomic force microscopy to stu...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952222/ https://ncbi.nlm.nih.gov/pubmed/17660745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601807 |
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