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PHF11 promotes DSB resection, ATR signaling, and HR
Resection of double-strand breaks (DSBs) plays a critical role in their detection and appropriate repair. The 3′ ssDNA protrusion formed through resection activates the ATR-dependent DNA damage response (DDR) and is required for DSB repair by homologous recombination (HR). Here we report that PHF11...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287112/ https://ncbi.nlm.nih.gov/pubmed/28115467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291807.116 |
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