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A noninvasive optical approach for assessing chloride extrusion activity of the K–Cl cotransporter KCC2 in neuronal cells
BACKGROUND: Cation-chloride cotransporters (CCCs) are indispensable for maintaining chloride homeostasis in multiple cell types, but K–Cl cotransporter KCC2 is the only CCC member with an exclusively neuronal expression in mammals. KCC2 is critical for rendering fast hyperpolarizing responses of ion...
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| 出版年: | BMC Neurosci |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286847/ https://ncbi.nlm.nih.gov/pubmed/28143398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0336-5 |
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