Coexpression and Heteromerization of Two Neuronal K-Cl Cotransporter Isoforms in Neonatal Brain

The neuron-specific K-Cl cotransporter KCC2 maintains the low intracellular chloride concentration required for the fast hyperpolarizing actions of inhibitory neurotransmitters. The KCC2 gene codes for two isoforms, KCC2a and KCC2b, which differ in their N termini. The relative expression and cellul...

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Autores principales: Uvarov, Pavel, Ludwig, Anastasia, Markkanen, Marika, Soni, Shetal, Hübner, Christian A., Rivera, Claudio, Airaksinen, Matti S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679471/
https://ncbi.nlm.nih.gov/pubmed/19307176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807366200
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