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Coexpression and Heteromerization of Two Neuronal K-Cl Cotransporter Isoforms in Neonatal Brain

The neuron-specific K-Cl cotransporter KCC2 maintains the low intracellular chloride concentration required for the fast hyperpolarizing actions of inhibitory neurotransmitters. The KCC2 gene codes for two isoforms, KCC2a and KCC2b, which differ in their N termini. The relative expression and cellul...

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Bibliografske podrobnosti
Main Authors: Uvarov, Pavel, Ludwig, Anastasia, Markkanen, Marika, Soni, Shetal, Hübner, Christian A., Rivera, Claudio, Airaksinen, Matti S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679471/
https://ncbi.nlm.nih.gov/pubmed/19307176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807366200
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