BDNF-induced TrkB activation down-regulates the K(+)–Cl(−) cotransporter KCC2 and impairs neuronal Cl(−) extrusion

Pathophysiological activity and various kinds of traumatic insults are known to have deleterious long-term effects on neuronal Cl(−) regulation, which can lead to a suppression of fast postsynaptic GABAergic responses. Brain-derived neurotrophic factor (BDNF) increases neuronal excitability through...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rivera, Claudio, Li, Hong, Thomas-Crusells, Judith, Lahtinen, Hannele, Viitanen, Tero, Nanobashvili, Avtandil, Kokaia, Zaal, Airaksinen, Matti S., Voipio, Juha, Kaila, Kai, Saarma, Mart
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173387/
https://ncbi.nlm.nih.gov/pubmed/12473684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados