Genetically engineered mouse models in oncology research and cancer medicine

Genetically engineered mouse models (GEMMs) have contributed significantly to the field of cancer research. In contrast to cancer cell inoculation models, GEMMs develop de novo tumors in a natural immune‐proficient microenvironment. Tumors arising in advanced GEMMs closely mimic the histopathologica...

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Bibliografische gegevens
Gepubliceerd in:EMBO Mol Med
Hoofdauteurs: Kersten, Kelly, de Visser, Karin E, van Miltenburg, Martine H, Jonkers, Jos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286388/
https://ncbi.nlm.nih.gov/pubmed/28028012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606857
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