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Non-germline genetically engineered mouse models for translational cancer research

Genetically engineered mouse models (GEMMs) of cancer have affected virtually all areas of cancer research. However, the accelerated discovery of new cancer genes emerging from large-scale cancer genomics and new chemical entities pouring from the drug discovery pipeline have strained the capacity o...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Heyer, Joerg, Kwong, Lawrence N., Lowe, Scott W., Chin, Lynda
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602412/
https://ncbi.nlm.nih.gov/pubmed/20574449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2877
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