Non-germline genetically engineered mouse models for translational cancer research

Genetically engineered mouse models (GEMMs) of cancer have affected virtually all areas of cancer research. However, the accelerated discovery of new cancer genes emerging from large-scale cancer genomics and new chemical entities pouring from the drug discovery pipeline have strained the capacity o...

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Udgivet i:Nat Rev Cancer
Main Authors: Heyer, Joerg, Kwong, Lawrence N., Lowe, Scott W., Chin, Lynda
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602412/
https://ncbi.nlm.nih.gov/pubmed/20574449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2877
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