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Genetically engineered mouse models in oncology research and cancer medicine

Genetically engineered mouse models (GEMMs) have contributed significantly to the field of cancer research. In contrast to cancer cell inoculation models, GEMMs develop de novo tumors in a natural immune‐proficient microenvironment. Tumors arising in advanced GEMMs closely mimic the histopathologica...

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Publicat a:EMBO Mol Med
Autors principals: Kersten, Kelly, de Visser, Karin E, van Miltenburg, Martine H, Jonkers, Jos
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286388/
https://ncbi.nlm.nih.gov/pubmed/28028012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606857
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