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Genetically engineered mouse models in oncology research and cancer medicine

Genetically engineered mouse models (GEMMs) have contributed significantly to the field of cancer research. In contrast to cancer cell inoculation models, GEMMs develop de novo tumors in a natural immune‐proficient microenvironment. Tumors arising in advanced GEMMs closely mimic the histopathologica...

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Détails bibliographiques
Publié dans:EMBO Mol Med
Auteurs principaux: Kersten, Kelly, de Visser, Karin E, van Miltenburg, Martine H, Jonkers, Jos
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286388/
https://ncbi.nlm.nih.gov/pubmed/28028012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606857
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