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Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models

Recent technological advances have opened the door for the fast and cost-effective generation of genetically engineered mouse models (GEMMs) to study cancer. We describe here a conceptually novel approach for the generation of chimeric GEMMs based on the controlled introduction of various genetic el...

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Detalhes bibliográficos
Main Authors: Huijbers, Ivo J, Krimpenfort, Paul, Berns, Anton, Jonkers, Jos
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179600/
https://ncbi.nlm.nih.gov/pubmed/21735458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201100018
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