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Genome-scale RNA interference screen identifies antizyme 1(OAZ1) as a target for improvement of recombinant protein production in mammalian cells()
For the purpose of improving recombinant protein production from mammalian cells, an unbiased, high-throughput whole-genome RNA interference screen was conducted using human embryonic kidney 293 (HEK 293) cells expressing firefly luciferase. 21,585 human genes were individually silenced with three d...
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| Vydáno v: | Biotechnol Bioeng |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283837/ https://ncbi.nlm.nih.gov/pubmed/27215166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26017 |
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