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Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells

The ability to produce recombinant proteins by utilizing different “cell factories” revolutionized the biotherapeutic and pharmaceutical industry. Chinese hamster ovary (CHO) cells are the dominant industrial producer, especially for antibodies. Human embryonic kidney cells (HEK), while not being as...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Inwood, Sarah, Betenbaugh, Michael J., Shiloach, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793178/
https://ncbi.nlm.nih.gov/pubmed/29315258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9010025
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