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Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells

The ability to produce recombinant proteins by utilizing different “cell factories” revolutionized the biotherapeutic and pharmaceutical industry. Chinese hamster ovary (CHO) cells are the dominant industrial producer, especially for antibodies. Human embryonic kidney cells (HEK), while not being as...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Inwood, Sarah, Betenbaugh, Michael J., Shiloach, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793178/
https://ncbi.nlm.nih.gov/pubmed/29315258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9010025
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