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Genome-scale RNA interference screen identifies antizyme 1(OAZ1) as a target for improvement of recombinant protein production in mammalian cells()
For the purpose of improving recombinant protein production from mammalian cells, an unbiased, high-throughput whole-genome RNA interference screen was conducted using human embryonic kidney 293 (HEK 293) cells expressing firefly luciferase. 21,585 human genes were individually silenced with three d...
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| 發表在: | Biotechnol Bioeng |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283837/ https://ncbi.nlm.nih.gov/pubmed/27215166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26017 |
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