The MMS22L–TONSL heterodimer directly promotes RAD51‐dependent recombination upon replication stress

Homologous recombination (HR) is a key pathway that repairs DNA double‐strand breaks (DSBs) and helps to restart stalled or collapsed replication forks. How HR supports replication upon genotoxic stress is not understood. Using in vivo and in vitro approaches, we show that the MMS22L–TONSL heterodim...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Piwko, Wojciech, Mlejnkova, Lucie J, Mutreja, Karun, Ranjha, Lepakshi, Stafa, Diana, Smirnov, Alexander, Brodersen, Mia ML, Zellweger, Ralph, Sturzenegger, Andreas, Janscak, Pavel, Lopes, Massimo, Peter, Matthias, Cejka, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283591/
https://ncbi.nlm.nih.gov/pubmed/27797818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593132
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