The MMS22L–TONSL heterodimer directly promotes RAD51‐dependent recombination upon replication stress

Homologous recombination (HR) is a key pathway that repairs DNA double‐strand breaks (DSBs) and helps to restart stalled or collapsed replication forks. How HR supports replication upon genotoxic stress is not understood. Using in vivo and in vitro approaches, we show that the MMS22L–TONSL heterodim...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Piwko, Wojciech, Mlejnkova, Lucie J, Mutreja, Karun, Ranjha, Lepakshi, Stafa, Diana, Smirnov, Alexander, Brodersen, Mia ML, Zellweger, Ralph, Sturzenegger, Andreas, Janscak, Pavel, Lopes, Massimo, Peter, Matthias, Cejka, Petr
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283591/
https://ncbi.nlm.nih.gov/pubmed/27797818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593132
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