The MMS22L–TONSL heterodimer directly promotes RAD51‐dependent recombination upon replication stress

Homologous recombination (HR) is a key pathway that repairs DNA double‐strand breaks (DSBs) and helps to restart stalled or collapsed replication forks. How HR supports replication upon genotoxic stress is not understood. Using in vivo and in vitro approaches, we show that the MMS22L–TONSL heterodim...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Piwko, Wojciech, Mlejnkova, Lucie J, Mutreja, Karun, Ranjha, Lepakshi, Stafa, Diana, Smirnov, Alexander, Brodersen, Mia ML, Zellweger, Ralph, Sturzenegger, Andreas, Janscak, Pavel, Lopes, Massimo, Peter, Matthias, Cejka, Petr
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283591/
https://ncbi.nlm.nih.gov/pubmed/27797818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593132
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