The MMS22L–TONSL heterodimer directly promotes RAD51‐dependent recombination upon replication stress

Homologous recombination (HR) is a key pathway that repairs DNA double‐strand breaks (DSBs) and helps to restart stalled or collapsed replication forks. How HR supports replication upon genotoxic stress is not understood. Using in vivo and in vitro approaches, we show that the MMS22L–TONSL heterodim...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Piwko, Wojciech, Mlejnkova, Lucie J, Mutreja, Karun, Ranjha, Lepakshi, Stafa, Diana, Smirnov, Alexander, Brodersen, Mia ML, Zellweger, Ralph, Sturzenegger, Andreas, Janscak, Pavel, Lopes, Massimo, Peter, Matthias, Cejka, Petr
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283591/
https://ncbi.nlm.nih.gov/pubmed/27797818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593132
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