The MMS22L–TONSL heterodimer directly promotes RAD51‐dependent recombination upon replication stress

Homologous recombination (HR) is a key pathway that repairs DNA double‐strand breaks (DSBs) and helps to restart stalled or collapsed replication forks. How HR supports replication upon genotoxic stress is not understood. Using in vivo and in vitro approaches, we show that the MMS22L–TONSL heterodim...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Piwko, Wojciech, Mlejnkova, Lucie J, Mutreja, Karun, Ranjha, Lepakshi, Stafa, Diana, Smirnov, Alexander, Brodersen, Mia ML, Zellweger, Ralph, Sturzenegger, Andreas, Janscak, Pavel, Lopes, Massimo, Peter, Matthias, Cejka, Petr
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283591/
https://ncbi.nlm.nih.gov/pubmed/27797818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593132
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