Peripheral apoE isoform levels in cognitively normal APOE ε3/ε4 individuals are associated with regional gray matter volume and cerebral glucose metabolism

BACKGROUND: Carriers of the APOE ε4 allele are at increased risk of developing Alzheimer’s disease (AD), and have been shown to have reduced cerebral metabolic rate of glucose (CMRgl) in the same brain areas frequently affected in AD. These individuals also exhibit reduced plasma levels of apolipopr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Nielsen, Henrietta M., Chen, Kewei, Lee, Wendy, Chen, Yinghua, Bauer, Robert J., Reiman, Eric, Caselli, Richard, Bu, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282900/
https://ncbi.nlm.nih.gov/pubmed/28137305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-016-0231-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados