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Is there a significant interaction between APOE rs405509 T/T, and e4 genotypes on cognitive impairment and gray matter volume?
BACKGROUND: Evidence demonstrates that the T allele of the single-nucleotide polymorphism rs405509 in the apolipoprotein E (APOE) promoter is a risk factor for Alzheimer’s disease (AD). However, it is unknown whether rs405509 T allele synergizes to the APOE ε4 allele in influencing cognition and bra...
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| Publicado en: | Eur J Neurol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987229/ https://ncbi.nlm.nih.gov/pubmed/27259692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ene.13052 |
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